BMC2 Data on In-Stent Restenosis Presented During the SCAI 2026 Scientific Sessions

Dr. Elias Dayoub presented "In-Stent Restenosis in Contemporary Clinical Practice: Incidence, Risk Factors, and Treatment Approaches – Insights From BMC2" during the Society for Cardiovascular Angiography and Interventions (SCAI) Scientific Sessions, April 23 - 25, 2026, in Montreal, Canada.

In-stent restenosis has remained a major long-term complication of PCI, and in-stent restenosis PCI represents a significant share of all PCIs performed.

Understanding the predictors and incidence of ISR, the time to late stent-related complications, and treatment patterns can help inform contemporary management of ISR. 

Dr. Dayoub looked at BMC2 data and Medicare claims data for PCIs performed in Michigan from 1/1/2014 through 9/30/2023 (with follow-up through 9/30/2024).

Takeaways:

•In comparison to older studies, the incidence of in-stent restenosis has declined in contemporary practice.

•The incidence of one-year target lesion revascularization rates is incrementally decreasing over time.

•Patient and anatomic risk factors had the greatest association with one-year target lesion revascularization rates